Hesperidin

Detailed Product Description

Hesperidin

CAS NO.:520-26-3

Other  names:Hesperetin-7-rhamnoglucoside, Cirmtin, Hesperetin-7-rutinoside

Chem. name: 4H-1-Benzopyran-4-one,7-[[6-O-(6-deoxy--L-mannopyranosyl)--D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methyoxyphenyl)-,(S)-

M.F. & M.W.: C28H34O15; 610.55

Physical properties: crystal in  the shape of tree branches (precipitation under pH6-7); M.P.: 258-262(softening point at 250); []20D: -76 degree (C=2, pyridine); solubility: 1 gram in 50 L of water; soluble in formamide and dimethyl formamide at 60; slightly soluble in methanol and hot glacial acetic acid; almost insoluble in acetone, benzene and chloroform; readily soluble in dilute base and pyridine Plant source: Galium  mollugo Linn., above ground part[1]; fruit of Citrus medica L. var.  sarcodactylis (Noot.) Swingle[2], C.tankan Hayata[3], Poncirus trifoliata(L.) Raf.[4], and Citrus limon Burm.[5]; C. limonia Osbeck., skin of the fruit; C. medica L., mature fruit[5]; Capsella  bursa-pastoris(L.) Me dic, whole plant including root[7].

Function and Applications:

1. Enhance  the action  of Vitamin C  [8]: relief the blood cell coaggualtion in conjunctiva of guinea pig due to lack of Vitamin C; it is also reported that it can reduce blood cell coaggualtion in horse. The life span of rats is prolonged [9] when the product is fed with thrombogenic feed or feed that may cause atherosis. Can raise the Vitamin C concentration in adrenal gland, spleen  and white blood cell in   guinea pig.[10]

2. Anti-viral  capability: when fibrocytes of mice are treated with the product in 200g/ml solution, the cells can resist the attack from phlyctenular stomatitis virus for 24 hours. HeLa cells treated with the product can resist  the infection from flu virus. The antiviral activity of the product may be attenuated by hyaluronidase [11]

3. Other: prevent injury from cold[12]; inhibit aldehyde reductase in lens of rat eyes[13].